Organophosphorus Insecticides

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Poisoning by organophosphorus insecticides and sensory neuropathy.

OBJECTIVES Poisoning by organophosphate insecticides causes cholinergic toxicity. Organophosphate induced delayed polyneuropathy (OPIDP) is a sensory-motor distal axonopathy which usually occurs after ingestion of large doses of certain organophosphate insecticides and has so far only been reported in patients with preceding cholinergic toxicity. Surprisingly, it was recently reported by other ...

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Effect of four organophosphorus insecticides on microbial activities in soil.

Laboratory tests were conducted with four organophosphorus insecticides, Bay 37289 (O-ethyl O-2,4,5-trichlorophenyl ethylphosphonothioate), diazinon [O,O-diethyl O-(2-isopropyl-4-methyl-6-pyrimidinyl) phosphorothioate], Dursban (O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate), and Zinophos (O,O-diethyl O-2-pyrazinyl phosphorothioate), applied to a sandy loam at rates of 10 and 100 mug...

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Mechanism of action of organophosphorus and carbamate insecticides.

Organophosphorus and carbamate insecticides are toxic to insects and mammals by virtue of their ability to inactivate the enzyme acetylcholinesterase. This review addresses the mechanism of inhibition of acetylcholinesterase by organophosphorus and carbamate esters, focusing on structural requirements necessary for anticholinesterase activity. The inhibition of acetylcholinesterase by these com...

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Organophosphorus insecticides affect normal polyamine metabolism in amphibian embryogenesis

a LIBIQUIMA, Facultad de Ingeniería, IDEPA, Universidad Nacional del Comahue – CONICET, Buenos Aires 1400, 8300 Neuquén, Argentina b Facultad de Ciencias Agrarias, Universidad Nacional del Comahue, Ruta 151 Km 12.5, 8303 Cinco Saltos, Río Negro, Argentina c Facultad de Ciencias Médicas, Universidad Nacional del Comahue, Toschi y Arrayanes, 8324 Cipolletti, Río Negro, Argentina d Laboratorio de ...

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Poisoning with the S-Alkyl organophosphorus insecticides profenofos and prothiofos

BACKGROUND Many organophosphorus (OP) insecticides have either two O-methyl or two O-ethyl groups attached to the phosphorus atom. This chemical structure affects their responsiveness to oxime-induced acetylcholinesterase (AChE) reactivation after poisoning. However, several OP insecticides are atypical and do not have these structures. AIM We aimed to describe the clinical course and respons...

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ژورنال

عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan

سال: 1960

ISSN: 0037-9980,1883-6526

DOI: 10.5059/yukigoseikyokaishi.18.531